Testosterone Injections

The most popular and cost-effective method of testosterone delivery

Why Injections?

Testosterone injections are the most widely prescribed form of TRT, used by approximately 70% of men on therapy. They offer the best combination of effectiveness, cost, and dosing control.

Unlike topical methods, injections deliver a precise dose directly into the body with no risk of transfer to partners, children, or pets.

Types of Injectable Testosterone

  • Testosterone Cypionate (Depo-Testosterone) — The most commonly prescribed in the US. Oil-based, with a half-life of 8-12 days. Typically injected weekly or every other week.
  • Testosterone Enanthate (Delatestryl) — Very similar to cypionate. Slightly shorter half-life. Popular in the US and Europe.
  • Testosterone Propionate — Shorter-acting (2-3 day half-life). Requires more frequent injections but provides very stable levels.
  • Testosterone Undecanoate (Aveed) — Long-acting injection given every 10 weeks. Administered in-office only.

Injection Methods

  • Intramuscular (IM) — Injected into the muscle (glutes, quads, delts). Uses a 1-1.5" needle. Most traditional method.
  • Subcutaneous (SubQ) — Injected into fat tissue (abdomen, love handles). Uses a small insulin needle (½-⅝"). Increasingly popular for its ease and less pain.

Many clinics now recommend subcutaneous injections for their convenience and more stable absorption rates.

Typical Protocol

  • Dose: 100-200mg per week (individualized based on blood work)
  • Frequency: 1-2 times per week for most stable levels
  • Needle size: 25-29 gauge (thin, minimal pain)
  • Self-injection: Most patients learn to inject at home after initial training

Your clinic will teach you proper injection technique and provide supplies. Most men become comfortable with self-injection within 2-3 tries.

What to Expect

After starting testosterone injections:

  • Week 1-2: Initial mood and energy improvements
  • Week 3-4: Libido begins to increase
  • Week 4-8: Body composition changes start (less fat, more muscle tone)
  • Month 3-6: Full effects realized — energy, mood, sexual function, body composition

Find a TRT clinic to discuss whether injections are right for you.